There are many HGH supplements on the market, but the only manufacturer that has taken the rare step of conducting a double blind clinical study was GenF20 Plus. The results were certainly worth discussing as this HGH supplement showed improvement in libido, energy, sleep and memory especially in those over forty years of age.
The 63-page, double blind study “GenF20 Plus in normal to overweight adult volunteers with poor quality of sleep, decreased memory, decreased libido and low energy levels.” Was carried out at Suhas Erande, Lokmanya Hospital, Supe Hospital, Medi Point Clinic, Akshay, 6 Hospital and Jeevan Rekha Hospital by the following researchers Dr. Pravin Supe, Dr. Rahul Patil, Dr. Vinayak Kale, and Dr. Shivram Bhonagiri. The study was carried out in accordance with all required study protocols and related laws.
The reason for the study was to look at how effective the GenF20 Plus supplement was on the users’ quality of life as it relates to energy, sleep, body weight, libido and memory.
GenF20 Plus was well tolerated by those participating in the study, and a clear increase in IGF-1 levels in the 40+ age participants was established. A boost in HGH and IGF-1 levels when using GenF20Plus shows this supplement could be helpful in slowing the aging process, and improving libido, sleep quality, lean muscle mass, libido, memory and physical stamina. The study was conducted over a 12-week period, and the promising results show how badly there is a need for a long-term study to determine what those changes would look like long term. Because improvements were seen in just 12 weeks the researchers believe that the improvements would continue over time and the results would be far more significant than what was seen in the 12 weeks.
The study was carried out in compliance with the Declaration of Helsinki, the US and International Good Clinical Practice Standards and the International Conference on Harmonization guidelines, the ICMR Ethical Guidelines for Biomedical Research on Human Participants, and the institutional research policies and procedures, along with all related government regulations.
The study was conducted hypothesizing that GenF20 Plus would promote the increased secretion of HGH in the anterior pituitary gland, which when released in the blood stream causes the liver to stimulate the production of IGF-1, which is the main intermediary of HGH effects. The study was conducted to determine the safety and effectiveness of GenF20 Plus related to improved IGF-1 levels, which in turn lead to quality of life improvements for the individuals who participated, which included improved sleep, memory, libido, energy levels and body weight.
In the active group, the serum IGF-1 levels from the baseline to the end of the treatment saw considerable increases compared to those who were in the placebo group that showed no statistically significant changes. It is an established scientific fact that IGF-1 levels decline as one ages. The GenF20 Plus group saw a noticeable increase in IGF-1 levels compared to what was established in the placebo group.
This major increase in the IGF-1 levels in the 40+ age of the active group can directly be linked to their taking GenF20 Plus. If the use of GenF20 Plus was extended long term, it is highly probable that researchers would see a further increase in IGF-1 levels. In the <40 age subgroup no marked changes were seen. This is likely because their body is still releasing normal levels of IGF-1 compared to those that are older than 40. Still it is highly recommended that a long term study be undertaken to establish the effectiveness and safety of GenF20 Plus use in the increasing IGF-1 levels in those who are 40+ years of age.
All of the participants no matter what their age tolerated GenF20 Plus well. There were 12 adverse events and 7 were in the active group while 5 were in the placebo group. In all cases, the adverse events were mild and not linked to the use of GenF20 Plus. All of the adverse events were resolved. There were no major changes in the vitals, routine urine tests, or hematology variables.
GenF20 Plus is a natural product with no serious side effects, that’s designed to help slow the aging process and boost body function. GenF20 Plus is not made to be used by those with a growth hormone deficiency. GenF20 Plus is designed to naturally increase HGH levels that have decreased with aging by stimulating the pituitary gland. There are few options on the market that have been shown to be safe when used to increase the body’s growth hormone levels, but GenF20 Plus has been proven to be a safe solution.
Athletes and body builders often use HGH and IGF 1 as performance enhancing agents, to increase their muscle mass and exercise endurance. There are a number of adverse effects that can happen that range from insulin disruption to cancer. Therefore, the use of HGH and IGF-I is not considered safe and safe alternatives need to be found.
An earlier study showed that HGH stimulates fat loss (lipolysis) in obese mice, which has lead to a decrease in total body weight. There have been other studies that have shown that HGH can lead to fat loss because it inhibits the adipocyte lipogenesis, which in turn will reduce fatty acid synthase and insulin sensitivity.
In the Rudman clinical study HGH was administered to a group of elderly healthy men that presented with low plasma IGF-I values and no core pituitary pathology. What it showed was that HGH had many beneficial effects. These studies confirm when an increase in IGF-I and HGH occurs in the body, it will stimulate the production of lipolysis, which will lead to a decrease in body fat.
In summary, while the predicted efficacy of GenF20 Plus wasn’t completely delivered due to the short period of the study, the results of this double blind clinical study proved there were many benefits to using the GenF20 Plus HGH supplement and that there is a need for further long term clinical studies to establish the long term benefits of use. This study shows the potential for GenF20 Plus to reduce body fat and overall weight, and improve the quality of life at any age.
Having an independent double blind study conducted on an HGH supplement seldom occurs – it’s rare because of the high cost and in some instances the known ineffectiveness of the products sold. The GenF20 Plus manufacturers should be commended for undertaking an expensive independent double blind study that has shown both the advantages and risks of taking Genf20 Plus.
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